Before You Start Retatrutide
Retatrutide is not an FDA-approved medication. It is a research peptide available through clinical trials or grey market vendors. Before using retatrutide, understand what you are getting into: the product is labeled for research use only, is not manufactured under regulated conditions, and carries no guarantees of purity or accurate dosing. The clinical trial data from Eli Lilly shows exceptional weight loss results — 28.3% average in the TRIUMPH-1 trial — but those results come from pharmaceutical-grade product, not grey market vials. This guide is for informed individuals who understand these risks.
Getting Started: What You Need
To start retatrutide you need four things: a vial of lyophilized retatrutide powder, a vial of bacteriostatic water, insulin syringes with 30- or 31-gauge needles, and alcohol swabs. The standard starting dose is 2 mg once weekly for the first 4 weeks. To prepare a 2 mg dose from a 10 mg vial reconstituted with 2 mL of bacteriostatic water, draw 40 units on a 100-unit insulin syringe. This is the starting dose used in the TRIUMPH clinical trials and is designed to minimize side effects during the adjustment period.
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