Monthly Cost at Different Dose Levels
The monthly cost of retatrutide depends on the weekly dose and the vendor pricing. At the starting dose of 2 mg weekly, one 10 mg vial lasts 5 weeks, making the monthly cost approximately -24 based on typical grey market pricing of -120 per vial. At 4 mg weekly, a 10 mg vial provides 2.5 doses, so the monthly cost is approximately -96. At 8 mg weekly, a 10 mg vial provides 1.25 doses, making the monthly cost approximately -192. At the full 12 mg maintenance dose, a user needs approximately 1.2 vials per week, for a monthly cost of approximately -576.
Comparing Monthly Cost to Approved GLP-1 Drugs
The monthly cost of grey market retatrutide at therapeutic doses is -576, which is lower than the list price of brand-name GLP-1 drugs — Ozempic lists at , Wegovy at ,350, and Zepbound at ,060. However, insurance coverage significantly reduces the out-of-pocket cost for approved drugs for many patients. Grey market retatrutide has no insurance option. When Eli Lilly brings retatrutide to market after FDA approval, the expected monthly cost is -1,200, comparable to their existing GLP-1 products.
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